CD3 Antikörper (FITC)
Kurzübersicht für CD3 Antikörper (FITC) (ABIN1819664)
Target
Alle CD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Raised against a peptide representing an invariant cytoplasmic sequence within the CD3epsilon chain recognizes human CD3epsilon. CD3 is a multimeric protein complex composed of four distinct polypeptide chains (epsilon, gamma, delta, zeta) that assemble and function as three pairs of dimers (epsilon-gamma, epsilon-delta, zeta-zeta,). The CD3 complex serves as a T cell co-receptor that associates non-covalently with the T cell receptor (TCR) , ,. CD3 is a defining feature of cells belonging to the T cell lineage and can therefore be used as T cell marker. Ashas been specifically raised against an epitope within the epsilon peptide chain, highly conserved among species clone CD3-12 has a very broad species cross-reactivity for the CD3 marker. ,.
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Aufreinigung
- Protein G purified
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Immunogen
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Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys). Percent identity by BLAST analysis: Chimpanzee, Gorilla, Ferret, Panda, Bovine, Dog, Cat, Opossum, Turkey, Chicken, Lizard (83%).
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG1
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Applikationshinweise
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Approved: Flo (1:5 - 1:10)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing. Protect from light.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- CD3
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Andere Bezeichnung
- CD3
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Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
Target
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